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Patients were ascertained from community and hospital psychiatric services nationally, private psychiatric hospitals, general practitioners and directly through local and national media

Irritability often serves as an important criterion in diagnosing various adolescent psychiatric disorders, such as anxiety disorders, depression disorder, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, autism spectrum disorder, conduct disorder, and bipolar disorder, defined as an abnormal response to adversity or threat in individuals 7

Avoid this combination if you have a severe cardiac history, including stroke or uncontrolled hypotension

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These tests were performed according to Finegold and Baron 14