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With respect to the newness criterion, according to the applicant, XENOVIEW TM was granted NDA approval from FDA on December 23, 2022 for the use of XENOVIEW TM (xenon Xe 129 hyperpolarized) with magnetic resonance imaging (MRI) for evaluation of lung ventilation in adults and pediatric patients aged 12 years and older

Research Protocol Suggested research protocol 1 Reconstitution Add 2ml bacteriostatic water to a 10mg vial for a concentration of 5mg/ml (5,000mcg/ml)

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Increased replicative capacity is linked to extended cellular lifespan in controlled laboratory conditions