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Accordingly, the HIV/AIDS public health community has made a concerted effort to examine the impact of stigma and embark on multipronged efforts to counter stigma with educational programs targeting specific vulnerable populations, in addition to addressing the role of health care professionals in exacerbating the effects of stigma [47]

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Mutationally activated KRAS is locked in its active form, resistant to the inactivating effects of GTPase-activating proteins, and cannot hydrolyze guanosine triphosphate to guanosine diphosphate

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