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This nuclear localization has particularly been observed in proliferating cells including a range of different cancers such as colorectal carcinoma, melanoma, uterine cervical neoplasms, breast cancer, and hepatocellular carcinoma

Gastrointestinal Endoscopy, 68(6), S54-S58

Irrespective, the TJ did not appear to be affected morphologically in these mice (of either sex) and the barrier function of the intestinal epithelium (small and large intestine), based on electrophysiological measurements, also appeared normal

Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

The peptide also activates alternative angiogenic pathways including VEGF-independent routes via Src-caveolin-1-eNOS signaling, providing redundant mechanisms for vascular regeneration