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Animals exposed to e-cigarettes had a particularly high level of cytokines interleukin 1 beta (IL-1) and tumor necrosis factor alpha (TNF-), compounds that may damage the delicate barrier that regulates the transport of nutrients between the eye and the bloodstream, the study authors wrote

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Either way, if the FDA is not provided with the regulatory tools to take appropriate enforcement action against these new and emerging products marketed as PMTA Exempt, the FDAs authority and its capability to protect public health are further undermined