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Notably, these effective concentrations were 16,000-80,000,000 times lower than concentrations of melatonin required for comparable effects, suggesting highly potent regulatory mechanisms rather than simple antioxidant activity
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As mentioned above, we explored the potential mechanisms of FA-induced system xCT suppression and found higher p53 activation in tubular cells induced by FA administration, while LA supplementation blocked the activity of p53 and abrogated the pro-ferroptosis effects
To view a copy of this licence, visit About this article Cite this article Bodard, S., Razakamanantsoa, L., Geevarghese, R
Thromb Haemost 2022;122:1061-70
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