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In the years following its introduction, millions of adult Japanese smokers switched to THS and other HTPs

It is available in nicotine strengths ranging from 0mg to 50mg

Tobacco corporations continue to manufacture market and sell a product that will kill millions

Follow-up systems toxicology studies showed that after 90 days of exposure, IQOS exposure, unlike CS exposure, did not lead to global miRNA downregulation while upregulating inflammation-related miRNA 71 and menthol IQOS has minimal effect on lung proteomes and lipidomes 72

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