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Known for its toasted tobacco, the brand gained immense popularity during the 1930s and 1940s

As well as having a higher risk of cancer death, people who smoke have double the risk of dying from stroke and heart disease

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PG/VG aerosols increase mucus concentration and MMP-9 activity in sheep in vivo Finally, to determine the effects of PG/VG e-cig aerosols in the airways in vivo, we used our previously established large animal (sheep) model and exposed sheep to 80 puffs per day (40 puffs per session twice daily) of PG/VG e-cig aerosols for five days (Fig