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In the legally prescribed International Organization of Standardization measurement method (ISO), in which air is mixed with the smoke through the ventilation holes, the connection is also visible, but less significant

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The exponential beta for the regression coefficient for light cigarette smokers and the log-normal morphology percentage was 0.66 (95% CI: 0.560.77), indicating that light cigarette smoking is associated with a 34% decrease in normal morphology