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EGCG from green tea inhibits STAT3 phosphorylation, attenuating downstream IL-17/IL-22 production ( in-vitro and animal models)

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Glutathione is synthesized in a two-step process, in which the first and rate-limiting enzyme -glutamylcysteine synthetase (ECS or GSH1) converts glutamate and cysteine to EC, then glutathione synthetase (GSH2) forms glutathione by the ligation of an additional glycine to the intermediate 42,43 (Fig

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In a clinical trial, pure genistein supplementation (54 mg/day, P.O for one year) improved both cardiac function and left atrial remodeling in postmenopausal women with metabolic syndrome [138]