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Drug or food interactions: Bile acid sequestrants decrease the ability of the body to absorb numerous drugs such as: warfarin (Coumadin), thyroid hormone, amiodarone, sulindac (Clinoril), methotrexate (Rheumatrex, Trexall), digoxin (Lanoxin), glipizide (Glucotrol), phenytoin (Dilantin), imipramine (Tofranil), niacin (Niacor, Niaspan, Slo-Niacin), methyldopa, tetracycline (Sumycin), clofibrate (Atromid-S), hydrocortisone, ezetimibe (Zetia), or penicillin

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Furthermore, Secondhand smoke exposure also leads to lung cancer and heart disease