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Because of cost and risk of adverse effects of the drugs they are normally only prescribed for severe cases of cold sore or for patients with immune suppression, Zoutman said

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- The SBT base, however, has been eroded over time reducing its neutrality and fairness

Mar Pollut Bull 165:112160 Fowles J, Dybing E (2003) Application of toxicological risk assessment principles to the chemical constituents of cigarette smoke