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In 1604, Englands James I wrote a manifesto against what he considered a loathsome and dangerous habit

95% less represents the average reduction in levels of a range of harmful chemicals, excluding nicotine, as compared to the smoke of a reference cigarette

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In general, smokers already face a heightened risk of catching viral infections, likely due to their having depressed immune systems , tissue damage and chronic inflammation in the respiratory tracts, Christenson added