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Nicotine can raise heart rate, increase adrenaline, and create sensations such as palpitations, jitteriness, chest tightness, or restlessness

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Age Young people, especially those under the age of 25, are at high risk of developing a first episode of cannabis-induced psychosis

Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses