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The low heterogeneity observed in studies on current users (I 2 = 0%) suggests consistent results, while the moderate heterogeneity for former and ever users emphasizes the need for further research to explore the complexities of e-cigarette exposure and its role in COPD development

2 As clinicians, we need to ascertain the patients readiness to quit and receptivity to standard therapies

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This discovery has led researchers to investigate the potential for cannabis to treat various pain conditions for which opioids are currently first- or second-line therapies