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The active ingredient in the Ueyamas invention was pyrethrum paste, a substance derived from chrysanthemum flowers, used as an insecticide for centuries in China and the Near East

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Over the last decades, novel nicotine and tobacco containing products such as electronic cigarettes (ECs) and heated tobacco products (HTPs) have been introduced to the market and marketed as safer options for smokers unable to quit conventional cigarettes (CCs) 3,4

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