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Acrolein is known to worsen pain by activating and causing a proliferation of pain receptors called TRPA1, or transient receptor potential ankyrin-1, found in nerve fibers

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For example, when asked whether he sells pan masala (gutka) alongside tobacco packets discreetly, given the ban on such products in Assam, Sale Uddin Lashkar, a middle-aged pan shop owner near Rajdhani School in Guwahati, responded candidly, I sell it the way I just gave you the packet

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Incredibly, you're also half as likely to get cancer of the mouth, throat, esophagus or bladder