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In the nucleus, following heterodimer complex formation with transcription factors, like small Maf proteins (G/F/K) and c-Jun, Nrf2 complexes bind to the antioxidant response element (ARE), a regulatory enhancer region within gene promoters that upregulate antioxidant and anti-inflammatory defense processes (Cuadrado et al., 2019
This set is intended for in vitro and preclinical research environments needing consistent research peptides, clear batch traceability, and UK supply standards across assay development, analytical verification, stability screening, and controlled laboratory evaluation
Proc Natl Acad Sci USA 116:26722680
Boivin J
