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Bee pollen (BP) is a valuable apitherapeutic product and is considered a nutritional healthy food appreciated by natural medicine from ancient times

Phenformin treatment significantly reduced viral replication, as shown by lower mean oropharyngeal viral titers in the Treated group (1.1 0.9 10 2 , 0.8 1.3 10 2 , 1.5 1.2 10 1 nsp14 copies/ng of RNA on D1, D2, and D3, respectively) compared to those of the Vehicle group

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Through the function of nuclear retinoic acid receptors, all-trans retinoic acid, 9-cis retinoic acid, or other metabolites, vitamin A plays an essential role in controlling innate and cell-mediated immunity and antibody response ( Table 1 )