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Global gene expression profiling of HLCs derived from differentiation Methods 1 and 2 was conducted using GeneChip PrimeView Human Gene Expression Arrays (Affymetrix

In the ferroptotic process, iron plays a pivotal role in several processes, including Fenton reaction-driven ROS production and the activation of key enzymes involved in lipid peroxidation, such as ALOX, NOX, and mitochondrial complexes I and III [103]

Wenke K , Meiser B , Thiery J , et al

Mice were subjected to CLP, then the kidneys were collected at the indicated time

Drugs which are available as over-the-counter supplements have the advantage of having a good safety profile [271], yet face one of the largest difficulties in translating to patients: the lack of financial support from commercial sponsors [272, 273]