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[2] Most carcinogens act by creating mutations in DNA that disrupt a cell's normal processes for regulating growth, leading to uncontrolled cellular proliferation

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Hatoun J, Davis-Plourde K, Penti B, Cabral H, Kazis L (2018) Tobacco control laws and pediatric asthma

I have always claimed that tobacco returns will generally generate a much greater variation across growers compared to many other agricultural enterprises given tobacco producer differences in labor source (H2A vs non-H2A), labor requirements, yield expectations, equipment and housing/stripping facilities, GAP fees, and price outcomes