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There, indigenous people had used it for centuries, either by inhalation, ingestion or topically, as a treatment for any number of illnesses like headaches, colds, sores and stomach upsets

Reversibility of the smokingcortical thickness association Controlling for pack-years, gender and exact age at scanning (Model 4), positive associations were shown between cortical thickness at age 73 years and number of years since smoking the last cigarette (Figure 4a and Supplementary Table S3)