In the present study, we systematically showed that ACTL6A functions as a regulator of GSH synthesis and then inhibits ferroptosis of GC cells in vitro and in vivo
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BALB/c mice immunized with the TSHR A-subunit plasmid developed TSHR/insulin-like growth factor 1 receptor (IGF-1R) antibodies, hypothyroidism, orbital inflammation, and proptosis, mimicking TAO [277]
Instead, it may be that chronic diseases cause low glutathione levels, which then can exacerbate the conditions due to an inability to counteract the increasing levels of oxidative stress
