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The Japanese military pursued this aim by distributing opium-based medicines and cigarettes

Cigarettes and e-cigarettes also both suppress respiratory immunity, making a user more likely to get sick Over 70% of e-cigarette liquids contain diacetyl, which has been shown to reduce lung capacity and cause irreversible respiratory diseases like bronchiolitis obliterans (popcorn lung)

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In addition, the smoking topography measures (total smoke volume, average puff volume, puff duration, inter-puff interval, and puffs per cigarette) were obtained from the CReSS device for each cigarette smoked during this study