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[50] [51] The attempt was postponed indefinitely after negative public feedback, with particular controversy generated on both sides by the disproportionate use by African-Americans

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There were similar rates of mild adverse events (e.g., nausea, restlessness, insomnia, irritability) across groups in trials of cytisine based on our initial overview.22 However, an updated Cochrane review on cytisine42 suggested there may be a small increase in adverse events, which could constitute a small harm (4 RCTs, n = 4052