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Sources CMS, FY2026 ICD-10-CM Code Descriptions and Tabular List (effective Oct 1, 2025) cms.gov/medicare/coding-billing/icd-10-codes (accessed 2026-06-12) CMS, FY2026 ICD-10-CM Official Guidelines for Coding and Reporting, Section I.C.5.b fy-2026-icd-10-cm-coding-guidelines.pdf (accessed 2026-06-12) CDC/NCHS, ICD-10-CM cdc.gov/nchs/icd/icd-10-cm (accessed 2026-06-12) Frequently Asked Questions What is the ICD-10 code for tobacco dependence

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The main inflammatory cytokines released upon cigarette smoking include IL (interleukin)-6, IL-1, IL-8 and CXCL-8, released by broncho-epithelial cells, and tumour necrosis factor-alpha (TNF-), nitric oxide (NO) and granulocyte macrophage-colony stimulating factor (GM-CSF), which are released by the macrophages in the alveolar space (Paudel et al., 2022c)