Nicotine salts vs freebase: You may want to regulate a bit using freebase nicotine, which absorbs more slowly
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Most available data reflect short-term observations, making it difficult to evaluate chronic effects on lung development or endurance capacity
It is therefore recommended to quit smoking as soon as possible
Nicotine Tob Res 12(2):179183 Chapman F, McDermott S, Rudd K et al (2022) A randomised, open-label, cross-over clinical study to evaluate the pharmacokinetic, pharmacodynamic and safety and tolerability profiles of tobacco-free oral nicotine pouches relative to cigarettes