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We downloaded the .tsv file of the PPI network obtained above, imported it into Cytoscape 3.7.0 software and analysed the data using the CytoNCA plug-in, filtering the core targets according to the degree greater than the median
A system transport present in the inner mitochondrial membrane, that involves dicarboxylate and 2-oxoglutarate anion transporters, allows the passage of negatively charged GSH from the cytosol to the mitochondria
Patients who already qualify for GLP-1 therapy and would like additional support Individuals with suboptimal B12 levels or risk of deficiency Those who prefer combining metabolic and micronutrient therapy Patients fully committed to close medical oversight and follow-up However, its not recommended if you have contraindications to GLP-1 agents, are pregnant, breastfeeding, have uncontrolled GI disease, or cannot adhere to monitoring and follow-up