En estudios preclnicos, BPC-157 promueve angiogenesis por las vas VEGFR2-Akt-eNOS (PMID 27847966) y Src-Cav-1-eNOS (PMID 33051481), ligadas al xido ntrico
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showed that in the absence of DNA, a member of the basic/helix-loop-helix/zipper family of DNA-binding proteins, transcription factor Max, is rapidly digested by several endoproteases, indicating an open and flexible structure of the protein in the unbound form (Cohen et al., 1995)
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More specifically, it interacts with serotonin receptors (5-HT1A/5-HT2), dopamine receptors, GABA balance, and the nitric oxide system