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Recent studies show that exposure to GLP1-RA in the first trimester is not associated with a risk of major birth defects when compared with diabetes or obesity

While human data remains limited, this area is attracting significant research attention particularly relevant in clinical settings where patients use multiple pharmaceuticals that carry hepatotoxic risk

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Pathologically, alveolar epithelial and pulmonary microvascular endothelial cells are damaged, and the permeability of microvascular basement membrane increases, leading to fluid accumulation in the interstitium or alveolar cavity [103]

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