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On top of that, herbal cigarette smoke had much higher oxidative potential, meaning it triggered more cell-damaging molecules associated with chronic diseases like lung disorders and heart disease.Leaf-wrapped herbal cigarettes, especially those using tendu leaves (like in bidis), were even more problematic, showing nearly a 50% higher oxidative potential than paper-wrapped ones

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Michael Grossman and Henry Saffer, Beer Taxes, the Legal Drinking Age, and Youth Motor Vehicle Fatalities, Journal of Legal Studies 16(2) (June 1987):351374