All patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or decreases [see Boxed Warning]
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striatum (caudate putamen, nucleus accumbens shell and core)
That switch may well avert a substantial portion of smoking-related deaths, but harm reduction is a difficult case to make in a field as ideologically driven as tobacco control
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