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These models incorporate spatial and temporal smoothing and a series of county- and state-level covariates to improve predictions for all counties, including those with limited data available in a given year from the BRFSS

Some of these may treat mental health problems that worsen CUD

Nicotine-induced epithelial-mesenchymal transition via Wnt/-catenin signaling in human airway epithelial cells

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Accessed February 19, 2014.] In 2013, states will collect $25.7 billion from tobacco taxes and legal settlements but are spending less than 2 percent of that on tobacco control programs.^[Campaign for Tobacco Free Kids