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Additionally, exogenous, infectious factors occurring locally (including infections), dietary factors (improper diet), psychogenic factors (stress), and atmospheric factors (sun, humidity, cold) may participate in the development of rosacea
[5] [6] Early-phase clinical trials including a Phase 2 trial published in the New England Journal of Medicine (2023) have reported significant reductions in body weight and improvements in metabolic markers, though this evidence remains preliminary and is not sufficient to establish a clinical dosing or reconstitution standard
Cell 93 (2), 189201
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