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There is credible laboratory evidence that nicotine interacts with nicotinic acetylcholine receptors in ways that may protect dopaminergic neurons, the neurons whose loss drives Parkinsons [14]

Available at, (Accessed: 13th April 2018)

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Hence, it is plausible that the MOE for alcohol can be lower than the one for heroin, purely because of the high exposure to alcohol in the European society (see also Rehm et al

The global herbal shisha segment is estimated to be growing at a CAGR exceeding 9.5% , albeit from a small base, signaling an important adjacent opportunity for established shisha tobacco manufacturers to diversify their product portfolios