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Faster enzymatic clearance through MEOS reduces peak BAC relative to intake volume once metabolic tolerance is established

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Antonoff MB, Ragalie W, Correa AM, Spicer JD, Sepesi B, Roth JA, Walsh GL, Wl H, Swisher SG , Rice DC, Vaporciyan AA, Mehran RJ

Following three washing steps with PBS, cells were permeabilized with 0.1% Triton for 20 min and blocked with 2% BSA in PBS-Tween (0.5%) at room temperature for at least 1 h

Results demonstrated significant improvements in sleep efficiency and subjective sleep quality ratings in the DSIP treatment group, with particular enhancement of the first sleep cycle and improved transition into slow-wave sleep