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doi:10.1371/journal.pmed.1000216

Specifications, Standards & Compliance Must meet ISO 9001:2015 quality management standards

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Another possibility is that there is a potent dose effect, supported by higher concentrations of e-cigarette vapor exposure in vitro causing suppression of HLA-DR (antigen presentation) and CD86 (costimulatory molecule important for T-cell activation) in LPS matured DCs, converting them from potent T-cell activators into tolerogenic or functionally impaired antigen-presenting cells