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We didnt find any significant differences between selegiline and placebo in terms of rates of smoking or changes in cravings or any other outcomes, says Ivan Montoya, Deputy Director at NIDAs Division of Pharmacotherapies and Medical Consequences of Drug Abuse We basically abandoned that compound and that approach, although there is still science showing that nicotine dependence may be associated with changes in monoamines in the brain, says Montoya

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