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Unexpectedly, CSE-EVs were associated with less robust colony formation suggestive of a net reduction in malignant transformation, potentially as a byproduct of the observation that these CSE-EV-treated urothelial cells grew more slowly and exhibited poorer viability than all other tested SV-HUC cells (data not shown)

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Data include 95% confidence intervals (95% CI), which indicate the uncertainty in an estimate