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Secretory IgA (sIgA) What it measures: Your gut's first line of immune defense

During deep sleep: Growth hormone secretion peaks, driving tissue repair and muscle recovery The brains glymphatic system clears metabolic waste products, including proteins associated with neurodegeneration Cortisol levels reach their daily minimum, allowing the adrenal system to reset Immune function regenerates Cellular repair mechanisms run at maximum efficiency Most adults spend less time in deep sleep than optimal, and this deficit increases with age, stress, alcohol consumption, and certain medications

TB-500, a synthesized fragment, mirrors many of TB4's systemic repair properties and is known to distribute broadly throughout the body, supporting healing across multiple tissue types simultaneously

Schaefer, L., & Iozzo, R