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Nature 606 , 791796 (2022)

These properties position THC as a promising candidate for depression intervention, though clinical translation requires further investigation

Hydration of skin and increased water retention

The approval was backed by the Phase II open-label AGAVE-201 trial, where treatment with a 0.3-mg/kg dose of Niktimvo elicited an overall response rate of 75%, with a median time to response of 1.5 months