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The environment and autoimmune thyroid diseases Eur J Endocrinol

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Smoking also influences immune regulation at a molecular signaling level

Another study found that acute exposure to 1-NPs (a PAH) increased pro-inflammatory cytokines and chemokines (such as IL-1, IL-6, TNF and keratinocyte chemoattractant [KC]) and activated PI3K/Akt signalling when administered intratracheally to wild type mice and also in human A549 cells [110]

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