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Targeting redox regulation appears to be an ideal approach to this disease yet challenging, possibly due to delicate redox balance, disparities between animal models and human diseases, species differences, compound bioavailability, and other variables

Clarifying the specific role of ferroptosis in the onset of atherosclerosis, as well as its role in other organ lesions, still requires attention and participation of more researchers

Nearly one in four participants lost more than a third of their body weight

doi: 10.3389/fimmu.2019.02285 15 TelangSClemBFKlarerACClemALTrentJOBucalaRet al