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Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination

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Because cysteine availability is the principal bottleneck in glutathione synthesis, increasing intracellular cysteine supply drives higher GSH production

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They are indicated for patients when a prescribing practitioner determines that the compounded preparation produces a significant difference for their patient compared to an FDA-approved product