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Single-cell RNA sequencing studies in murine smoke models have identified an excessive influx of monocyte-derived macrophage subset population responsible for heightened inflammation and ECM remodeling, a finding that has also been validated in emphysematous COPD patients 59

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Mary Jo Henry, ARNP, UnityPoint Health, explains secondhand smoke effects, how it impacts pregnancy and children and when you should consider changing your routine to avoid secondhand smoke