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On the right side is a graphic of a gradient pink brain with green signal lines that look like electrical shocks running through the front of the brain

(Source Fischer et al., 2020[3]) Contribution of smoking to the total economic costs of addictions If we consider the costs of tobacco use in relation to those of alcohol and illegal drugs, the share of direct and indirect tobacco costs represents some 54% [4] of the total costs of addictions, according to the Human Capital calculation method, or 51%[5] of the total costs using the Friction Costs method (or 49% if the estimated costs of gambling are also considered[6])

Lancet 340(8828):11111115 Celermajer DS et al (1993) Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults

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