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The blood-brain-barrier can be crossed by Trp, but not by serotonin (206)

Alpern 1997

The American Journal of Gastroenterology, 113 (11), 1701

In a large study in more than 5000 participants with type 2 diabetes, it was shown that poor glycaemic control was associated with anhedonia but not depression or anxiety [119], suggesting that anhedonia may be more important than general depression scores