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Protection Against Muscle Damage and Dystrophy IGF-1 LR3 exhibits protective effects against contraction-induced muscle injury, particularly relevant in muscular dystrophy pathophysiology

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UCP2 is a member of inner mitochondrial membrane proteins that dissipates the mitochondrial proton gradient by transporting H + across the inner membrane, thereby generating heat, stabilizing the inner mitochondrial membrane potential and reducing the formation of ROS (Pierelli et al

It was originally studied for gastrointestinal healing but researchers quickly identified potent effects on connective tissue, tendons, ligaments, and joints

The above results suggest that PL may induce ferroptosis