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7 However, decreased CYP2A6 activity may influence smoking and carcinogen exposure in any smoker, and the relationship of nicotine metabolism and CYP2A6 genotype to the lung cancer risk of smokers of European descent was recently established in the Transdisciplinary Research in Cancer of the Lung consortium genome-wide association study data set

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According to anecdotes from WWII, the Charminar cigarette brand gained a household name in India when the troops stationed there developed a strong affinity for them

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Some studies have modeled the relation between cotinine concentrations and cigarette consumption by taking into account several of these variables