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Individual susceptibility is a function of cellular susceptibility, metabolic activation of the precarcinogen, catabolic destruction of the carcinogen, DNA susceptibility, and DNA repair (see 8 for review, Figure 3)

Every 10% increase in the price of cigarettes reduces youth consumption by 7% and another study found that a $2 increase per pack could reduce consumption by 40%

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The FDA (in charge of tobacco control in the US) is currently working on regulations to reduce nicotine levels in cigarettes to non-addictive levels, aiming to reduce smoking rates and prevent new addictions, improving public health